Women needed for clinical trial to improve endometriosis treatment

Tuesday, September 12, 2017

Are you due to have a laparoscopy for symptoms suggestive of endometriosis?

The PRE-EMPT Research Study is currently seeking patients.  The study is a large national clinical trial trying to find out if long acting progestogen treatment (either Mirena Coil® or  Depo-Provera® ) is more effective compared to the oral contraceptive pill in preventing the recurrence of symptoms and improving quality of life.

The target population is women of reproductive age with laparoscopically diagnosed endometriosis, who have undergone conservative surgery for alleviation of pelvic pain, and who have no contraindications to any of the proposed hormonal treatments.

The treatments offered in PRE-EMPT are:-

  • Mirena Coil / Levosert

  • Depo-Provera

  • Combined oral contraceptive pill

You may be eligible to take part in the PRE-EMPT trial if you

  • Are aged between 16-45 years

  • Have no immediate plans to conceive (not currently planning a pregnancy)

  • Are scheduled to have laparoscopy with concurrent surgery for pelvic pain associated with endometriosis

  • Willing to be randomised (treatment randomly selected by a computer) to either a long acting progestogen treatment (you can choose between Mirena® or Depo-provera®.and be randomised with the combined oral contraceptive

 

What the trial involves

We will collect information on your pain, physical and emotional wellbeing  at the beginning of the study.  A similar questionnaire will then be sent to you at home at 6 months, then 1, 2 and 3 years after treatment.  The questions are designed to find out if there are any improvements or changes in your symptoms following treatment.  You are free to withdraw or change treatments at any point during the trial.

 

How to get involved

For more information about the hospitals recruiting and how to get in touch with us please contact Laura Gennard, Senior Trial Coordinator

Tel:  +44 (0)121 415 9109: email:  pre-empt@trials.bham.ac.uk: web: birmingham.ac.uk/pre-empt

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