Women needed for clinical trial to improve endometriosis treatment
Are you due to have a laparoscopy for symptoms suggestive of endometriosis?
Please note, all participants for this trial have now been recruited.
The study is a large national clinical trial trying to find out if long acting progestogen treatment (either Mirena Coil® or Depo-Provera® ) is more effective compared to the oral contraceptive pill in preventing the recurrence of symptoms and improving quality of life.
The target population is women of reproductive age with laparoscopically diagnosed endometriosis, who have undergone conservative surgery for alleviation of pelvic pain, and who have no contraindications to any of the proposed hormonal treatments.
The treatments offered in PRE-EMPT are:-
Mirena Coil / Levosert
Combined oral contraceptive pill
You may be eligible to take part in the PRE-EMPT trial if you
Are aged between 16-45 years
Have no immediate plans to conceive (not currently planning a pregnancy)
Are scheduled to have laparoscopy with concurrent surgery for pelvic pain associated with endometriosis
Willing to be randomised (treatment randomly selected by a computer) to either a long acting progestogen treatment (you can choose between Mirena® or Depo-provera®.and be randomised with the combined oral contraceptive
What the trial involves
We will collect information on your pain, physical and emotional wellbeing at the beginning of the study. A similar questionnaire will then be sent to you at home at 6 months, then 1, 2 and 3 years after treatment. The questions are designed to find out if there are any improvements or changes in your symptoms following treatment. You are free to withdraw or change treatments at any point during the trial.
All participants for this trial have now been recruited.
How to get involved
For more information about the hospitals recruiting and how to get in touch with us please contact the PRE-EMPT team.
Tel: +44 (0)121 415 9109: email: firstname.lastname@example.org: web: birmingham.ac.uk/pre-empt